Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14832796 | 0.91 | SNCA (0.53) | SNCAPTGS2MAPTALDH1A1POLB | |
| SCHEMBL23448488 | 0.91 | SNCA (0.53) | SNCAMAPTALDH1A1ESR1ESR2 | |
| SCHEMBL14838327 | 0.85 | SNCA (0.47) | SNCAMAPTALDH1A1POLBIKBKB | |
| SCHEMBL23447120 | 0.85 | SNCA (0.47) | SNCAMAPTALDH1A1POLBIKBKB | |
| SCHEMBL14832844 | 0.83 | SNCA (0.46) | SNCAMAPTALDH1A1POLBESR1 | |
| SCHEMBL11525285 | 0.81 | ESR1 (0.56) | SNCAPTGS2MAPTALDH1A1POLB | |
| SCHEMBL16021757 | 0.80 | SNCA (0.46) | SNCAESR1ESR2PTPN1 | |
| SCHEMBL14832510 | 0.74 | IKBKB (0.42) | SNCAMAPTALDH1A1POLBIKBKB | |
| SCHEMBL28848007 | 0.74 | ESR1 (0.43) | SNCAMAPTALDH1A1ESR1ESR2 | |
| SCHEMBL20147055 | 0.74 | ESR1 (0.43) | SNCAMAPTALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |