Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.35 |
| ▸ | TUBB | P07437 | 3/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811389 | 0.88 | NPC1 (0.42) | ESR1ESR2SNCAALDH1A1KDM4E | |
| SCHEMBL27797494 | 0.84 | IKBKB (0.40) | SNCAALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL6812091 | 0.83 | MAPT (0.40) | ESR1ESR2ALDH1A1KDM4ENPC1 | |
| SCHEMBL20147055 | 0.83 | ESR1 (0.43) | ESR1ESR2SNCAALDH1A1TUBB4A | |
| SCHEMBL12876559 | 0.82 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL23448488 | 0.82 | SNCA (0.53) | ESR1ESR2SNCAALDH1A1TUBB4A | |
| SCHEMBL566698 | 0.81 | APP (0.55) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5690630 | 0.81 | APP (0.47) | SNCAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9034233 | 0.80 | GSK3B (0.45) | KDM4ENPC1RAB9AMAPTLMNA | |
| SCHEMBL28896944 | 0.80 | CYP2A6 (0.41) | SNCAALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892588-B | Photochromic indazole thiophene hybrid-type perfluorinated cyclopentene compound and its synthetic method and application | 江西科技师范大学 | 2017-07-07 | — | — | CN | disclosed |