Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848007 | 0.83 | ESR1 (0.43) | ESR1ESR2SNCAALDH1A1KDM4E | |
| SCHEMBL23448488 | 0.82 | SNCA (0.53) | ESR1ESR2SNCAALDH1A1KDM4E | |
| SCHEMBL3594365 | 0.79 | IKBKB (0.42) | SNCAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL14832510 | 0.79 | IKBKB (0.42) | SNCAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL14832718 | 0.79 | PRKDC (0.40) | SNCAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL14832862 | 0.79 | APP (0.57) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14838409 | 0.78 | HSD17B1 (0.41) | ESR1ESR2SNCAALDH1A1KDM4E | |
| SCHEMBL14832870 | 0.75 | ALDH1A1 (0.41) | SNCAALDH1A1MAPTTDP1 | |
| SCHEMBL20146977 | 0.74 | SNCA (0.46) | ESR1ESR2SNCAALDH1A1KDM4E | |
| SCHEMBL16798610 | 0.74 | GSK3B (0.39) | SNCAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |