Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14838521 | 0.94 | ESR1 (0.41) | ESR1ESR2APP | |
| SCHEMBL6735028 | 0.94 | APP (0.40) | APP | |
| SCHEMBL16021763 | 0.81 | ESR1 (0.44) | ESR1ESR2 | |
| SCHEMBL5466664 | 0.80 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL21695432 | 0.78 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL3472776 | 0.77 | ESR2 (0.46) | ESR1ESR2APP | |
| SCHEMBL20527880 | 0.77 | APP (0.39) | APP | |
| SCHEMBL423920 | 0.77 | PLA2G10 (0.41) | ESR1ESR2 | |
| SCHEMBL3851690 | 0.77 | ESR1 (0.30) | ESR1ESR2 | |
| SCHEMBL14838335 | 0.76 | ESR1 (0.44) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |