SCHEMBL423920

SCHEMBL423920

Cc1sc(-c2ccccc2)cc1C1=C(c2cc(-c3ccccc3)sc2C)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.41
PTP4A3 O75365 2/20 0.39
PTP4A2 Q12974 1/20 0.37
PTP4A1 Q93096 1/20 0.37
RAB9A P51151 5/20 0.37
SMN1; SMN2 Q16637 5/20 0.37
ALDH1A1 P00352 5/20 0.37
NPC1 O15118 4/20 0.37
HPGD P15428 4/20 0.37
LMNA P02545 2/20 0.37
HSD17B1 P14061 3/20 0.36
MAPT P10636 7/20 0.33
KDM4E B2RXH2 3/20 0.33
PKM P14618 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
GAA P10253 4/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
HSD17B10 Q99714 2/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13164291 0.92 ESR1 (0.42) PLA2G10LMNAHSD17B1MAPTKDM4E
SCHEMBL23169718 0.92 PLA2G10 (0.37) PLA2G10PTP4A3PTP4A2PTP4A1RAB9A
SCHEMBL3008443 0.91 PLA2G10 (0.38) PLA2G10PTP4A3PTP4A2PTP4A1RAB9A
SCHEMBL15255340 0.90 PLA2G10 (0.38) PLA2G10PTP4A3PTP4A2PTP4A1RAB9A
SCHEMBL20024254 0.89 PLA2G10 (0.36) PLA2G10PTP4A3PTP4A2PTP4A1RAB9A
SCHEMBL23158842 0.89 PLA2G10 (0.38) PLA2G10PTP4A3PTP4A2PTP4A1RAB9A
SCHEMBL13163335 0.89 PLA2G10 (0.38) PLA2G10PTP4A3PTP4A2PTP4A1RAB9A
SCHEMBL3361316 0.89 PLA2G10 (0.36) PLA2G10PTP4A3PTP4A2PTP4A1RAB9A
SCHEMBL5466664 0.87 ESR1 (0.36) PLA2G10HSD17B1HSD17B2ESR1ESR2
SCHEMBL23246441 0.87 PLA2G10 (0.41) PLA2G10PTP4A3RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12311040-B2 Photonic structure for dynamic expression of colors and effects L'OREAL (FR) 2025-05-27 US claimed
US-20230000731-A1 PHOTONIC STRUCTURE FOR DYNAMIC EXPRESSION OF COLORS AND EFFECTS L'OREAL (FR) 2023-01-05 US claimed
US-11544876-B2 Integrated cosmetic design applicator L'OREAL (FR) 2023-01-03 US claimed
WO-2022232404-A1 INTEGRATED COSMETIC DESIGN APPLICATOR L'OREAL (FR) 2022-11-03 WO claimed
US-20220351414-A1 INTEGRATED COSMETIC DESIGN APPLICATOR L'OREAL (FR) 2022-11-03 US claimed
US-20020007072-A1 Photochromic reaction occurs in crystalline state; useful in optical recording media, display panels, sensors, optical switch devices due to variation in color, refractive idex, and permeability with light irradiation/phase change JAPAN SCIENCE AND TECHNOLOGY CORPORATION 2002-01-17 US claimed
EP-1167487-A1 ORGANIC MATERIAL UNDERGOING LIGHT-INDUCED PHASE TRANSITION Japan Science and Technology Corporation (JP) 2002-01-02 EP claimed
EP-3732533-B1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL LTD (IE) 2025-12-10 EP disclosed
US-20250262138-A1 HAIR DYE COMPOSITION PROCTER & GAMBLE (US) 2025-08-21 US disclosed
US-12329838-B1 Hair dye composition THE PROCTER & GAMBLE COMPANY (US) 2025-06-17 US disclosed
US-12311040-B2 Photonic structure for dynamic expression of colors and effects L'OREAL (FR) 2025-05-27 US disclosed
US-20250114289-A1 HAIR DYE COMPOSITION THE PROCTER & GAMBLE COMPANY 2025-04-10 US disclosed
WO-2025076185-A1 ARRAY OF HAIR DYE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2025-04-10 WO disclosed
US-20040008612-A1 Optical storage medium RAKUTEN GROUP, INC. (JP) 2004-01-15 US disclosed
US-6660868-B2 Photo-induced phase transition organic material JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-12-09 US disclosed
EP-1367111-A1 PHOTOCHROMIC MATERIAL Japan Science and Technology Corporation (JP) 2003-12-03 EP disclosed
EP-1346224-A1 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE Tibotec BVBA (BE) 2003-09-24 EP disclosed
WO-2002033419-A1 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE TIBOTEC BVBA (BE) 2002-04-25 WO disclosed
US-20020007072-A1 Photochromic reaction occurs in crystalline state; useful in optical recording media, display panels, sensors, optical switch devices due to variation in color, refractive idex, and permeability with light irradiation/phase change JAPAN SCIENCE AND TECHNOLOGY CORPORATION 2002-01-17 US disclosed
EP-1167487-A1 ORGANIC MATERIAL UNDERGOING LIGHT-INDUCED PHASE TRANSITION Japan Science and Technology Corporation (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007072-A1 Photochromic reaction occurs in crystalline state; useful in optical recording media, display panels, sensors, optical switch devices due to variation in color, refractive idex, and permeability with light irradiation/phase change CRY1, DDX1, DDX3X PLA2G10 3699/4885PTP4A3 2761/4885PTP4A2 2821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.