Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.40 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.39 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.37 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916777 | 0.89 | HSD17B1 (0.47) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL10002017 | 0.81 | HSD17B1 (0.41) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL14838323 | 0.81 | HSD17B1 (0.41) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL14838322 | 0.81 | HSD17B1 (0.43) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL14838325 | 0.80 | HSD17B1 (0.38) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL16021787 | 0.79 | HSD17B1 (0.40) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL14838518 | 0.78 | HSD17B1 (0.42) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL14838269 | 0.78 | HSD17B1 (0.42) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL14838329 | 0.78 | HSD17B1 (0.39) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL14838519 | 0.78 | HSD17B1 (0.39) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |