Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146985 | 0.78 | — | — | |
| SCHEMBL15183074 | 0.77 | TNKS (0.34) | — | |
| SCHEMBL17617006 | 0.76 | — | — | |
| SCHEMBL16021792 | 0.75 | CHEK1 (0.41) | CHEK1HRH3 | |
| SCHEMBL15275316 | 0.74 | CHEK1 (0.31) | CHEK1 | |
| SCHEMBL20146986 | 0.73 | KDM4E (0.34) | — | |
| SCHEMBL17617001 | 0.72 | KDM4E (0.33) | CHEK1 | |
| SCHEMBL10002014 | 0.71 | PRKDC (0.34) | — | |
| SCHEMBL15275315 | 0.69 | NCF1 (0.31) | — | |
| SCHEMBL17617023 | 0.67 | HSD11B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |