Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016643 | 0.86 | HCRTR1 (0.56) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2013106 | 0.84 | HCRTR1 (0.57) | HCRTR1HCRTR2NPC1RAB9AMEN1 | |
| SCHEMBL2015866 | 0.83 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2015169 | 0.82 | HCRTR1 (0.65) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2010631 | 0.82 | HCRTR1 (0.65) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2011481 | 0.82 | HCRTR1 (0.60) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2015192 | 0.80 | HCRTR1 (0.56) | HCRTR1HCRTR2NPC1RAB9AMEN1 | |
| SCHEMBL2016148 | 0.80 | HCRTR1 (0.56) | HCRTR1HCRTR2NPC1RAB9AKMT2A | |
| SCHEMBL2013232 | 0.80 | HCRTR1 (0.63) | HCRTR1HCRTR2NPC1RAB9ATP53 | |
| SCHEMBL2010730 | 0.80 | HCRTR1 (0.58) | HCRTR1HCRTR2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |