Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940138 | 0.76 | — | — | |
| SCHEMBL27726578 | 0.66 | ALDH1A1 (0.46) | ALDH1A1KMT2AHPGDTDP1POLB | |
| SCHEMBL461696 | 0.63 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDTDP1POLB | |
| SCHEMBL1177894 | 0.62 | POLB (0.62) | ALDH1A1KMT2AHPGDTDP1POLB | |
| SCHEMBL1782631 | 0.61 | POLB (0.56) | ALDH1A1KMT2AHPGDTDP1POLB | |
| SCHEMBL9141580 | 0.61 | — | — | |
| SCHEMBL28852941 | 0.61 | MAPT (0.52) | ALDH1A1KMT2AHPGDTDP1POLB | |
| SCHEMBL12464054 | 0.61 | GAA (0.54) | ALDH1A1KMT2AHPGDTDP1POLB | |
| SCHEMBL4056038 | 0.61 | GAA (0.54) | ALDH1A1KMT2AHPGDTDP1POLB | |
| SCHEMBL1177395 | 0.61 | POLB (1.00) | ALDH1A1KMT2AHPGDTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073929-A1 | 6-(2-FURYL)-3-METHYL-4-OXO-1,5,6,7-TETRAHYDROINDOLE-2-CARBOXYLATE DERIVATIVES AND USES THEREOF | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2011-06-23 | — | — | WO | disclosed |