Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464054 | 1.00 | GAA (0.54) | GAAKMT2APOLBMAPTTDP1 | |
| SCHEMBL28919464 | 0.78 | ALDH1A1 (0.56) | GAAKMT2APOLBMAPTTDP1 | |
| SCHEMBL27843146 | 0.71 | GAA (1.00) | GAAKMT2APOLBMAPTTDP1 | |
| SCHEMBL10794871 | 0.69 | ADORA2B (0.55) | GAAKMT2APOLBTDP1KDM4E | |
| SCHEMBL1177894 | 0.69 | POLB (0.62) | GAAKMT2APOLBMAPTTDP1 | |
| SCHEMBL5799723 | 0.68 | CHRM5 (0.46) | GAAKMT2APOLBMAPTTDP1 | |
| SCHEMBL28852941 | 0.68 | MAPT (0.52) | GAAKMT2APOLBMAPTTDP1 | |
| SCHEMBL1177395 | 0.68 | POLB (1.00) | GAAKMT2APOLBMAPTTDP1 | |
| SCHEMBL6181015 | 0.67 | CHRM5 (1.00) | CHRM5CHRM3CHRM1CHRM2CHRM4 | |
| SCHEMBL31087350 | 0.67 | CHRM5 (0.53) | GAAKMT2APOLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118750-A1 | STEREOSELECTIVE HYDROLYSIS FOR THE RESOLUTION OF RACEMIC MIXTURES OF (+/-) -CIS-S-ACETOXY-L- (4-METHOXYPHENYL) -4- (2-FURYL) -2-AZETIDINONE, (+/-) -CIS-S-ACETOXY-L- (4-METHOXYPHENYL) -4- (2-THIENYL) -2-AZETIDINONE, OR | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-10-01 | — | — | WO | disclosed |
| US-5177201-A | Nitrogen deprotected 4-acyloxyazetidin-2-ones | MERCK & CO., INC. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5177201-A | Nitrogen deprotected 4-acyloxyazetidin-2-ones | MERCK & CO., INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0404583-A3 | PROCESS FOR THE PREPARATION OF 4-ACYLOXYAZETIDIN-2-ONE BY ELECTROCHEMICAL METHODS | MERCK & CO. INC. (US) | 1992-01-02 | — | — | EP | disclosed |
| EP-0404584-A3 | OXIDATION AND REDUCTION METHOD TO PRODUCE 4-ACYLOXYAZETIDIN-2-ONE | MERCK & CO. INC. (US) | 1992-01-02 | — | — | EP | disclosed |
| EP-0404585-A3 | PROCESS FOR THE PREPARATION OF 4-ACYLOXYAZETIDIN-2-ONE BY SINGLET OXYGEN OXIDATION | MERCK & CO. INC. (US) | 1992-01-02 | — | — | EP | disclosed |
| EP-0404586-A3 | NITROGEN DEPROTECTED 4-ACYLOXYAZETIDIN-2-ONES | MERCK & CO. INC. (US) | 1991-12-11 | — | — | EP | disclosed |
| EP-0404584-A2 | Oxidation and reduction method to produce 4-acyloxyazetidin-2-one | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404584-A2 | Oxidation and reduction method to produce 4-acyloxyazetidin-2-one | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404585-A2 | Process for the preparation of 4-acyloxyazetidin-2-one by singlet oxygen oxidation | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404586-A2 | Nitrogen deprotected 4-acyloxyazetidin-2-ones | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404583-A2 | Process for the preparation of 4-acyloxyazetidin-2-one by electrochemical methods | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404583-A2 | Process for the preparation of 4-acyloxyazetidin-2-one by electrochemical methods | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404585-A2 | Process for the preparation of 4-acyloxyazetidin-2-one by singlet oxygen oxidation | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4952288-A | Process for the preparation of 4-acyloxyazetidin-2-one by electrochemical methods | MERCK & CO., INC. (US) | 1990-08-28 | — | — | US | disclosed |
| US-4952288-A | Process for the preparation of 4-acyloxyazetidin-2-one by electrochemical methods | MERCK & CO., INC. (US) | 1990-08-28 | — | — | US | disclosed |
| US-4940520-A | Process for the preparation of 4-acyloxyazetidin-2-one by singlet oxygen oxidation | MERCK & CO., INC. (US) | 1990-07-10 | — | — | US | disclosed |
| US-4940520-A | Process for the preparation of 4-acyloxyazetidin-2-one by singlet oxygen oxidation | MERCK & CO., INC. (US) | 1990-07-10 | — | — | US | disclosed |
| US-4923982-A | Oxidation and reduction method to produce 4-acyloxyazetidin-2-one | MERCK & CO., INC. (US) | 1990-05-08 | — | — | US | disclosed |
| US-4923982-A | Oxidation and reduction method to produce 4-acyloxyazetidin-2-one | MERCK & CO., INC. (US) | 1990-05-08 | — | — | US | disclosed |