Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150887 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL20150817 | 0.90 | EPAS1 (0.35) | TSHRHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL20148155 | 0.90 | EPAS1 (0.35) | TSHRHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL19216538 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL28153812 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL9947778 | 0.81 | EPAS1 (0.36) | CYP3A4MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9947775 | 0.81 | EPAS1 (0.36) | CYP3A4MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30975522 | 0.81 | MAPT (0.33) | MAPTNPC1RAB9ASMN1; SMN2EPAS1 | |
| SCHEMBL29303368 | 0.81 | MAPT (0.33) | MAPTNPC1RAB9ASMN1; SMN2EPAS1 | |
| SCHEMBL30975537 | 0.81 | MAPT (0.33) | MAPTNPC1RAB9ASMN1; SMN2EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134696-A1 | Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors | FORUM PHARMACEUTICALS, INC. | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134696-A1 | Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors | CHRNA7, CHRNA5, CHRNA2 | ALDH1A1 2821/4885TSHR 808/4885HSD17B10 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.