Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919598 | 0.84 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7063038 | 0.81 | TSHR (0.44) | TSHRTHRBCA2CA1TDP1 | |
| SCHEMBL665126 | 0.81 | TSHR (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11528787 | 0.81 | TSHR (0.61) | TSHRTHRBCA2CA1POLB | |
| SCHEMBL7803930 | 0.77 | TSHR (0.40) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23494244 | 0.77 | TSHR (0.55) | TSHRTHRBCA2CA1POLB | |
| SCHEMBL7126454 | 0.77 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8965485 | 0.77 | THRB (0.53) | TSHRTHRBCA2CA1POLB | |
| SCHEMBL11526952 | 0.76 | TSHR (0.64) | TSHRTHRBCA1POLBAPEX1 | |
| SCHEMBL1897951 | 0.76 | TSHR (0.58) | TSHRTHRBCA2CA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134983-A1 | ULTRA-FLUID LUBRICATING COMPOSITION | TOTALENERGIES ONETECH (FR) | 2018-05-17 | — | — | US | disclosed |