SCHEMBL8919598

SCHEMBL8919598

C=C(C)C(=O)OCCCCC(C)CC(C)(C)CCCOC(=O)C(=C)C

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.38
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20148190 0.84 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7803930 0.81 TSHR (0.40) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2907312 0.81 CHRNB2 (0.40) TSHRTDP1
SCHEMBL16864559 0.79 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL21579582 0.78 THRB (0.32) TSHRTHRB
SCHEMBL7126454 0.78 TSHR (0.43) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6066276 0.77 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11532326 0.77 TSHR (0.64) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28018815 0.77 TSHR (0.64) TSHRTHRBPOLBAPEX1HTT
SCHEMBL457682 0.77 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240164994-A1 ION SUSTAINED-RELEASE COMPOSITE PARTICLES AND METHOD OF PRODUCING ION SUSTAINED-RELEASE COMPOSITE PARTICLES GC CORPORATION (JP) 2024-05-23 US disclosed
EP-4316454-A1 ION SUSTAINED-RELEASE COMPOSITE PARTICLE AND METHOD FOR MANUFACTURING ION SUSTAINED-RELEASE COMPOSITE PARTICLE GC Corporation (JP) 2024-02-07 EP disclosed
WO-2023248838-A1 COMPOSITION FOR THREE-DIMENSIONAL MODELING AND METHOD FOR PRODUCING DENTAL MODELED OBJECT 株式会社ジーシー 2023-12-28 WO disclosed
EP-3342393-B1 DENTAL CEMENT G C DENTAL IND CORP (JP) 2023-11-29 EP disclosed
CN-113677309-A Two-component curable dental composition 株式会社GC 2021-11-19 CN disclosed
CN-113444204-A Dental polymerizable composition 株式会社GC 2021-09-28 CN disclosed
US-20210276243-A1 THREE-DIMENSIONAL PRINTING COMPOSITION AND METHOD OF PRODUCING DENTAL ARTICLE GC CORPORATION (JP) 2021-09-09 US disclosed
CN-107427414-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2021-07-02 CN disclosed
CN-112940432-A Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2021-06-11 CN disclosed
EP-3825099-A1 COMPOSITION FOR THREE-DIMENSIONAL SHAPING AND METHOD FOR PRODUCING DENTAL ARTICLE GC Corporation (JP) 2021-05-26 EP disclosed
CN-107920959-B Dental polymerizable composition 株式会社GC 2020-10-02 CN disclosed
WO-2020017122-A1 COMPOSITION FOR THREE-DIMENSIONAL SHAPING AND METHOD FOR PRODUCING DENTAL ARTICLE 株式会社ジーシー 2020-01-23 WO disclosed
US-10470981-B2 Dental cement GC CORPORATION (JP) 2019-11-12 US disclosed
US-20190008730-A1 DENTAL CEMENT GC CORPORATION (JP) 2019-01-10 US disclosed
EP-3342393-A1 DENTAL CEMENT GC Corporation (JP) 2018-07-04 EP disclosed
US-5698611-A ACRYLATED ESTER GC CORPORATION (JP) 1997-12-16 US disclosed