SCHEMBL20148875

SCHEMBL20148875

CCN(CC)c1ccc(C(c2ccc(Cl)cc2)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 9/20 0.53
GRK6 P43250 1/20 0.49
ALDH1A1 P00352 3/20 0.47
TSHR P16473 2/20 0.47
PSMD14 O00487 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.47
GFER P55789 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CNR1 P21554 4/20 0.46
CYP19A1 P11511 2/20 0.45
MAPT P10636 1/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131813 0.89 ALDH1A1 (0.56) CNR2GRK6ALDH1A1TSHRPSMD14
SCHEMBL2881066 0.87 CNR2 (0.63) CNR2ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL10876579 0.86 CNR2 (0.53) CNR2CNR1
SCHEMBL10355544 0.85 CNR2 (0.50) CNR2ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL5010085 0.84 TSHR (0.62) CNR2ALDH1A1TSHRMAPK1TDP1
Trimethylammonium SCHEMBL6555079 0.83 CNR2 (0.59) CNR2ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL6344469 0.83 CNR2 (0.59) CNR2ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL109699 0.82 CNR2 (0.53) CNR2GRK6ALDH1A1TSHRPSMD14
SCHEMBL9699686 0.82 SLC2A1 (0.55) CNR2GRK6ALDH1A1TSHRPSMD14
SCHEMBL9658375 0.82 GRK6 (0.54) CNR2GRK6ALDH1A1TSHRPSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10274874-B2 Intermediate transfer member, method for producing intermediate transfer member, and image forming apparatus Konica Minolta, Inc. (JP) 2019-04-30 US disclosed
US-20180136590-A1 INTERMEDIATE TRANSFER MEMBER, METHOD FOR PRODUCING INTERMEDIATE TRANSFER MEMBER, AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2018-05-17 US disclosed
US-20180136590-A1 INTERMEDIATE TRANSFER MEMBER, METHOD FOR PRODUCING INTERMEDIATE TRANSFER MEMBER, AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2018-05-17 US disclosed