SCHEMBL6344469

SCHEMBL6344469

CCN(CC)c1ccc(N(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.59
ALDH1A1 P00352 3/20 0.54
GFER P55789 2/20 0.54
PSMD14 O00487 1/20 0.54
CYP3A4 P08684 1/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
RECQL P46063 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CNR1 P21554 8/20 0.51
ALDH3A1 P30838 1/20 0.50
ALDH1A3 P47895 1/20 0.50
MAPT P10636 1/20 0.49
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL10535102 0.98 CNR2 (0.58) CNR2ALDH1A1GFERPSMD14CYP3A4
SCHEMBL2881066 0.95 CNR2 (0.63) CNR2ALDH1A1GFERPSMD14CYP3A4
Trimethylammonium SCHEMBL6555079 0.91 CNR2 (0.59) CNR2ALDH1A1GFERPSMD14CYP3A4
SCHEMBL1972710 0.87 ALDH1A1 (0.67) CNR2ALDH1A1GFERPSMD14CYP3A4
SCHEMBL332675 0.87 ALDH1A1 (0.67) CNR2ALDH1A1GFERPSMD14CYP3A4
SCHEMBL20148875 0.83 CNR2 (0.53) CNR2ALDH1A1GFERPSMD14CYP3A4
SCHEMBL8746233 0.83 CNR2 (0.53) CNR2ALDH1A1GFERPSMD14CYP3A4
SCHEMBL666720 0.82 LMNA (0.57) CNR2ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL1735497 0.82 ALDH1A1 (0.74) CNR2ALDH1A1GFERPSMD14CYP3A4
SCHEMBL9161116 0.80 ALDH1A1 (0.58) CNR2ALDH1A1GFERPSMD14CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001068740-A1 CHARGE TRANSPORT MATERIALS AVECIA LIMITED (GB) 2001-09-20 WO claimed
US-6858703-B2 Compound, compositions and use AVECIA LIMITED (GB) 2005-02-22 US disclosed
US-20040054095-A1 Compound, compositions and use AVECIA LIMITED OF BLACKLEY (GB) 2004-03-18 US disclosed
US-6630566-B1 Polymeric material comprising at least one repeat unit, the or each (if more than one) repeat unit consisting substantially of a moiety of Formula I:For photocopiers AVECIA LIMITED (GB) 2003-10-07 US disclosed
EP-1040152-B1 POLYMERIC MATERIAL COMPRISING N, P, S, AS OR SE AND COMPOSITION FOR CHARGE TRANSPORT MATERIAL AVECIA LTD (GB) 2002-10-16 EP disclosed
WO-2001068740-A1 CHARGE TRANSPORT MATERIALS AVECIA LIMITED (GB) 2001-09-20 WO disclosed