SCHEMBL20148917

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23510580	0.84	AR (0.31)	ARGUCY1A1GUCY1B1KCNH2
	SCHEMBL20148879	0.83	AR (0.41)	ARGUCY1A1GUCY1B1KCNH2ALDH1A1
	SCHEMBL21564207	0.80	AR (0.39)	ARGUCY1A1GUCY1B1KCNH2ALDH1A1
	SCHEMBL20148877	0.80	AR (0.39)	ARGUCY1A1GUCY1B1KCNH2ALDH1A1
	SCHEMBL20148902	0.80	HIF1A (0.43)	ARGUCY1A1GUCY1B1KCNH2ALDH1A1
	SCHEMBL20148918	0.80	AR (0.40)	ARGUCY1A1GUCY1B1KCNH2ALDH1A1
	SCHEMBL21564211	0.78	AR (0.38)	ARGUCY1A1GUCY1B1KCNH2ALDH1A1
	SCHEMBL20148878	0.76	PIM1 (0.43)	ARGUCY1A1GUCY1B1KCNH2ALDH1A1
	SCHEMBL29757105	0.72	RIPK1 (0.49)	ARALDH1A1KDM4EMEN1KMT2A
	SCHEMBL21787231	0.71	AR (0.36)	ARGUCY1A1GUCY1B1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.