Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.84 |
| ▸ | NR1I2 | O75469 | 7/20 | 0.68 |
| ▸ | TACR1 | P25103 | 3/20 | 0.58 |
| ▸ | TACR2 | P21452 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713056 | 0.91 | RORC (1.00) | RORCNR1I2TACR1 | |
| SCHEMBL23713117 | 0.82 | RORC (1.00) | RORCNR1I2TACR1 | |
| SCHEMBL20149031 | 0.81 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL20149245 | 0.81 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL20149055 | 0.81 | RORC (0.56) | RORCNR1I2 | |
| SCHEMBL20149129 | 0.80 | RORC (0.80) | RORCNR1I2TACR1TACR2 | |
| SCHEMBL20139742 | 0.79 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL20149057 | 0.78 | RORC (1.00) | RORCNR1I2TACR1 | |
| SCHEMBL23713066 | 0.76 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL15751783 | 0.76 | TACR1 (0.70) | RORCTACR1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |