Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.80 |
| ▸ | TACR1 | P25103 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713056 | 0.89 | RORC (1.00) | RORCTACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20149050 | 0.80 | RORC (0.84) | RORCTACR1NR1I2TACR2 | |
| SCHEMBL20149126 | 0.80 | RORC (0.83) | RORCNR1I2 | |
| SCHEMBL23713117 | 0.78 | RORC (1.00) | RORCTACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20149032 | 0.72 | RORC (0.58) | RORCTACR1 | |
| SCHEMBL20149057 | 0.72 | RORC (1.00) | RORCTACR1NR1I2 | |
| SCHEMBL4144315 | 0.72 | TACR1 (0.78) | RORCTACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4144312 | 0.72 | TACR1 (0.78) | RORCTACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4483139 | 0.72 | TACR1 (0.67) | RORCTACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4483149 | 0.72 | TACR1 (0.67) | RORCTACR1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |