Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.83 |
| ▸ | NR1I2 | O75469 | 10/20 | 0.77 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713035 | 0.91 | RORC (1.00) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL23713039 | 0.87 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL23713082 | 0.87 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL23713094 | 0.83 | RORC (1.00) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL20149245 | 0.83 | RORC (1.00) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL20149031 | 0.83 | RORC (1.00) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL20149129 | 0.80 | RORC (0.80) | RORCNR1I2 | |
| SCHEMBL23713148 | 0.79 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL23713003 | 0.79 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL23713009 | 0.75 | RORC (1.00) | RORCNR1I2NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |