Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.57 |
| ▸ | AR | P10275 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | IL5 | P05113 | 1/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149521 | 1.00 | PGR (0.57) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL20149273 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL20149154 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL20149523 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL20149269 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL20149153 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL20223502 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL20149524 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL22961128 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR | |
| SCHEMBL20149272 | 0.87 | NR3C1 (0.76) | PGRNR3C1CYP3A4ABCB11AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089373-A9 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018089373-A2 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |