SCHEMBL20149201

SCHEMBL20149201

Cc1ccccc1-c1c2cc3c(cc2c(-c2ccccc2C)c2c4ccc5c6c(ccc(c12)c64)-c1ccccc1-5)c1ccc2c4c(ccc3c41)-c1ccc(C#N)cc1-2

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
LRRK2 Q5S007 1/20 0.31
PDK2 Q15119 1/20 0.31
PARP14 Q460N5 1/20 0.31
BTK Q06187 1/20 0.31
DPP4 P27487 1/20 0.30
EGLN2 Q96KS0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22727720 0.88 PARP14 (0.33) PARP14
SCHEMBL23805917 0.86 ATM (0.35) ARCYP11B1CYP11B2PDK2PARP14
SCHEMBL23805918 0.83 AR (0.36) ARLRRK2
SCHEMBL20149202 0.79 AR (0.34) ARLRRK2
SCHEMBL10038784 0.78 MEN1 (0.42) DPP4
SCHEMBL23806109 0.77
SCHEMBL23081551 0.74 PARP14 (0.33) PARP14
SCHEMBL17487146 0.73 CA1 (0.39) CYP11B1CYP11B2EGLN2
SCHEMBL17490285 0.73 CA1 (0.39) CYP11B1CYP11B2
SCHEMBL17487145 0.73 CA1 (0.39) CYP11B1CYP11B2EGLN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11128791-B2 Photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-11121182-B2 Organic photoelectric conversion element, optical area sensor, image pickup device, and image pickup apparatus CANON KABUSHIKI KAISHA (JP) 2021-09-14 US disclosed
US-10468614-B2 Photoelectric conversion element, image pick-up element, and image pick-up apparatus CANON KABUSHIKI KAISHA (JP) 2019-11-05 US disclosed
US-20190267411-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS CANON KABUSHIKI KAISHA (JP) 2019-08-29 US disclosed
US-20190267545-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND IMAGING ELEMENT AND IMAGING APPARATUS INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2019-08-29 US disclosed
US-20180138432-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICK-UP ELEMENT, AND IMAGE PICK-UP APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-05-17 US disclosed
US-20180138432-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICK-UP ELEMENT, AND IMAGE PICK-UP APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190267545-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND IMAGING ELEMENT AND IMAGING APPARATUS INCLUDING THE SAME CPNE4, LEF1, EMC1 AR 4149/4885CYP11B1 848/4885CYP11B2 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.