Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.66 |
| ▸ | TACR1 | P25103 | 4/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148899 | 0.85 | RORC (0.72) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL20148976 | 0.84 | RORC (0.57) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL20149241 | 0.84 | RORC (0.57) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL16070094 | 0.82 | RORC (0.55) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL16032347 | 0.82 | RORC (0.55) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL3993928 | 0.82 | RORC (0.55) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL12513594 | 0.81 | RORC (0.54) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL1971296 | 0.81 | RORC (0.54) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL12587287 | 0.81 | RORC (0.54) | RORCTACR1PDE4BHDAC1HDAC2 | |
| SCHEMBL528565 | 0.81 | RORC (0.54) | RORCTACR1PDE4BHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |