Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 6/20 | 0.65 |
| ▸ | LGALS9 | O00182 | 5/20 | 0.65 |
| ▸ | LGALS1 | P09382 | 5/20 | 0.65 |
| ▸ | LGALS7; LGALS7B | P47929 | 4/20 | 0.65 |
| ▸ | LGALS8 | O00214 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21059437 | 0.93 | LGALS9 (0.55) | LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8 | |
| SCHEMBL15481915 | 0.91 | USP2 (0.56) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPOLB | |
| SCHEMBL15482001 | 0.91 | USP2 (0.56) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPOLB | |
| SCHEMBL14356282 | 0.89 | LGALS9 (0.54) | LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8 | |
| SCHEMBL10359946 | 0.88 | LGALS9 (0.53) | LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8 | |
| SCHEMBL10359947 | 0.88 | LGALS9 (0.53) | LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8 | |
| SCHEMBL11175487 | 0.88 | LGALS9 (0.54) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPOLB | |
| SCHEMBL11175481 | 0.88 | LGALS9 (0.54) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPOLB | |
| SCHEMBL27988153 | 0.86 | LGALS9 (0.53) | LGALS3LGALS9LGALS1LGALS7; LGALS7BALDH1A1 | |
| SCHEMBL15481791 | 0.86 | LGALS9 (0.51) | LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10441564-B2 | Fructose analogs and their combinations as anti-cancer agents | Jia, Wei (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180133192-A1 | Fructose analogs and their combinations as anti-cancer agents | JIA, WEI | 2018-05-17 | — | — | US | disclosed |
| US-20180133192-A1 | Fructose analogs and their combinations as anti-cancer agents | JIA, WEI | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133192-A1 | Fructose analogs and their combinations as anti-cancer agents | ALDOA, FBP1, MPI | LGALS3 31/4885LGALS9 118/4885LGALS1 34/4885 |
| US-10441564-B2 | Fructose analogs and their combinations as anti-cancer agents | ALDOA, FBP1, MPI | LGALS3 28/4885LGALS9 110/4885LGALS1 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.