Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044905 | 0.90 | HTR2C (0.57) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL30748760 | 0.90 | HTR2C (0.57) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL6089160 | 0.88 | HTT (0.47) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL6087581 | 0.84 | HTT (0.43) | SMN1; SMN2HTTNPC1RAB9AHTR2C | |
| SCHEMBL21100002 | 0.83 | PDK1 (0.49) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL3605859 | 0.82 | SMN1; SMN2 (0.50) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL20129643 | 0.82 | PARP1 (0.55) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL2820733 | 0.82 | PARP1 (0.55) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL13681760 | 0.82 | PARP1 (0.55) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL14348081 | 0.80 | SMN1; SMN2 (0.49) | PDK1PDK2PDK3PDK4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |