Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681760 | 1.00 | PARP1 (0.55) | PARP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL2820733 | 1.00 | PARP1 (0.55) | PARP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL6487540 | 0.96 | PDK1 (0.53) | PARP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL15298945 | 0.96 | PDK1 (0.53) | PARP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL1288345 | 0.96 | PDK1 (0.53) | PARP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL21809245 | 0.94 | PARP1 (0.51) | PARP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL30289174 | 0.93 | PARP1 (0.57) | PARP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL15606326 | 0.93 | PARP1 (0.57) | PARP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL8487526 | 0.91 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AHTTPDK1 | |
| SCHEMBL6335353 | 0.90 | PARP1 (0.54) | PARP1SMN1; SMN2NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271961-A1 | Pan-Tropic Entry Inhibitors | UNIV EMORY (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230271961-A1 | Pan-Tropic Entry Inhibitors | UNIV EMORY (US) | 2023-08-31 | — | — | US | disclosed |
| US-11649235-B2 | Pan-tropic entry inhibitors | EMORY UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| US-11649235-B2 | Pan-tropic entry inhibitors | EMORY UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| US-20210017178-A1 | Pan-Tropic Entry nhibitors | UNIV EMORY (US) | 2021-01-21 | — | — | US | disclosed |
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2020-07-02 | — | — | US | disclosed |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649235-B2 | Pan-tropic entry inhibitors | CXCR4, CCR5, CXCL12 | PARP1 630/4885SMN1; SMN2 2765/4885NPC1 134/4885 |
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | PARP1 718/4885SMN1; SMN2 3158/4885NPC1 1719/4885 |
| US-20210017178-A1 | Pan-Tropic Entry nhibitors | CXCR4, CXCL12, CCR5 | PARP1 473/4885SMN1; SMN2 2390/4885NPC1 166/4885 |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | PARP1 718/4885SMN1; SMN2 3158/4885NPC1 1719/4885 |
| US-20230271961-A1 | Pan-Tropic Entry Inhibitors | CXCR4, CCR5, CXCL12 | PARP1 555/4885SMN1; SMN2 2404/4885NPC1 192/4885 |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | PARP1 718/4885SMN1; SMN2 3158/4885NPC1 1719/4885 |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | PARP1 718/4885SMN1; SMN2 3158/4885NPC1 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.