Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129732 | 0.85 | SSTR2 (0.47) | CYP3A4CYP2C9SSTR2SSTR3CYP2C19 | |
| SCHEMBL20129616 | 0.79 | KDM4E (0.56) | ARMEN1KMT2ACHRM4RCE1 | |
| SCHEMBL20133861 | 0.71 | MTOR (0.50) | CHRM4KCNH2 | |
| SCHEMBL240298 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL14000091 | 0.68 | KDM4E (0.44) | MEN1KMT2ACHRM4ALDH1A1KDM4E | |
| SCHEMBL430414 | 0.67 | MAPT (0.43) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1692184 | 0.66 | GRM5 (0.38) | ARMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10819380 | 0.66 | GAA (0.58) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL13176022 | 0.66 | MEN1 (0.59) | ARMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16404655 | 0.66 | MEN1 (0.52) | ARMEN1KMT2ACHRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |