Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129624 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1SSTR2 | |
| SCHEMBL5793581 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2TSHRHPGD | |
| SCHEMBL20150131 | 0.79 | AR (0.45) | KDM4EALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL20141837 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL20140934 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1C5AR1L3MBTL1DPP4 | |
| SCHEMBL30561230 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10AR | |
| SCHEMBL30561225 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10AR | |
| SCHEMBL13176022 | 0.76 | MEN1 (0.59) | KDM4EALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL29678185 | 0.75 | LMNA (0.47) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL20133633 | 0.74 | KCNA3 (0.49) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | KDM4E 253/4885ALDH1A1 3942/4885SMN1; SMN2 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.