Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.60 |
| ▸ | CA1 | P00915 | 10/20 | 0.60 |
| ▸ | CA9 | Q16790 | 6/20 | 0.60 |
| ▸ | CA12 | O43570 | 4/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.58 |
| ▸ | CA5A | P35218 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354878 | 0.84 | CA2 (0.59) | CA2CA1CA9CA12CA6 | |
| SCHEMBL7991708 | 0.81 | CA2 (0.56) | CA2CA1CA9CA12CA6 | |
| SCHEMBL3811394 | 0.80 | L3MBTL1 (0.60) | CA2CA1CA9CA12CA6 | |
| SCHEMBL3763309 | 0.79 | CA2 (0.60) | CA2CA1CA9CA12CA6 | |
| SCHEMBL3813975 | 0.78 | L3MBTL1 (0.63) | CA2CA1CA9CA12CA6 | |
| SCHEMBL22499523 | 0.78 | L3MBTL1 (0.63) | CA2CA1CA9CA12CA6 | |
| SCHEMBL4734339 | 0.78 | CA2 (0.57) | CA2CA1CA9CA12CA6 | |
| SCHEMBL3661739 | 0.77 | CA2 (0.56) | CA2CA1CA9CA12CA6 | |
| SCHEMBL28984186 | 0.76 | PTGES2 (0.58) | CA2CA1CA9CA12CA6 | |
| SCHEMBL25465864 | 0.75 | CA2 (0.55) | CA2CA1CA9CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |