Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 6/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20114562 | 0.95 | CHEK1 (0.40) | CHEK1GRM2FLT3CYP11B1CYP11B2 | |
| SCHEMBL20114689 | 0.95 | PTGER4 (0.36) | CHEK1GRM2MAPKAPK2FLT3PTGER4 | |
| SCHEMBL20114543 | 0.92 | CHEK1 (0.36) | CHEK1ALDH1A1CYP11B1CYP11B2CSNK1A1 | |
| SCHEMBL20150354 | 0.92 | CHEK1 (0.34) | CHEK1GRM2FLT3ITKCYP11B1 | |
| SCHEMBL20150372 | 0.92 | CYP11B2 (0.34) | CHEK1GRM2ITKALDH1A1CYP11B1 | |
| SCHEMBL20115142 | 0.91 | CHEK1 (0.34) | CHEK1CYP11B1CYP11B2PTGER4 | |
| SCHEMBL22268469 | 0.91 | CHEK1 (0.36) | CHEK1GRM2MAPKAPK2FLT3ITK | |
| SCHEMBL20150391 | 0.91 | CHEK1 (0.36) | CHEK1GRM2MAPKAPK2FLT3ITK | |
| SCHEMBL20114547 | 0.91 | MAPKAPK2 (0.37) | CHEK1GRM2MAPKAPK2FLT3ITK | |
| SCHEMBL20114637 | 0.91 | ITK (0.38) | GRM2ITKALDH1A1CYP2A6CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421746-B2 | Organic molecules, especially for use in organic optoelectronic devices | CYNORA GMBH (DE) | 2019-09-24 | — | — | US | disclosed |
| US-20180134686-A1 | ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2018-05-17 | — | — | US | disclosed |
| US-20180134686-A1 | ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134686-A1 | ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | OR10J3, EPCAM, F12 | CHEK1 2795/4885GRM2 1828/4885MAPKAPK2 3348/4885 |
| US-10421746-B2 | Organic molecules, especially for use in organic optoelectronic devices | OR10J3, EPCAM, F12 | CHEK1 2795/4885GRM2 1828/4885MAPKAPK2 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.