Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | CDC25A | P30304 | 3/20 | 0.36 |
| ▸ | CDC25B | P30305 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12390086 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTHPGDHSD17B10MGLL | |
| SCHEMBL29201828 | 0.80 | HPGD (0.55) | SMN1; SMN2MAPTHPGDHSD17B10MGLL | |
| SCHEMBL10700265 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTHPGDHSD17B10MGLL | |
| SCHEMBL12755467 | 0.79 | NR1H2 (0.44) | MAPTHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL31121202 | 0.77 | MEN1 (0.54) | MAPTHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1395738 | 0.77 | ALDH1A1 (0.57) | SMN1; SMN2MAPTHPGDHSD17B10MGLL | |
| SCHEMBL780107 | 0.76 | MAPT (0.50) | SMN1; SMN2MAPTHPGDHSD17B10MGLL | |
| SCHEMBL576091 | 0.76 | MAPT (0.50) | SMN1; SMN2MAPTHPGDHSD17B10MGLL | |
| SCHEMBL9655918 | 0.76 | MAPT (0.50) | SMN1; SMN2MAPTHPGDHSD17B10MGLL | |
| SCHEMBL28372919 | 0.76 | HPGD (0.50) | SMN1; SMN2MAPTHPGDHSD17B10MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134845-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180134845-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134845-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | CD44, PGLS, HPSE | SMN1; SMN2 2957/4885MAPT 1122/4885HPGD 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.