Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150590 | 0.99 | LTA4H (0.47) | LTA4HHTR2AS1PR2S1PR1S1PR3 | |
| SCHEMBL7791938 | 0.84 | GRIN2D (0.40) | LTA4HHTR2AS1PR2S1PR1S1PR3 | |
| SCHEMBL7791941 | 0.84 | GRIN2D (0.40) | LTA4HHTR2AS1PR2S1PR1S1PR3 | |
| SCHEMBL7791209 | 0.83 | GRIN2D (0.41) | LTA4HHTR2AS1PR2S1PR1S1PR3 | |
| SCHEMBL7791211 | 0.83 | GRIN2D (0.41) | LTA4HHTR2AS1PR2S1PR1S1PR3 | |
| SCHEMBL10523570 | 0.81 | RARB (0.45) | LTA4HSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9818048 | 0.81 | SMPD1 (0.51) | HTR2AS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9399009 | 0.81 | SMN1; SMN2 (0.50) | HTR2AS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL19796690 | 0.81 | BIRC5 (0.44) | HTR2AS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL27574511 | 0.80 | GAA (0.39) | HTR2AHTR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134960-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134960-A1 | LIQUID-CRYSTAL MEDIUM | FES, POF1B, FOXO3 | LTA4H 4010/4885HTR2A 2253/4885S1PR2 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.