Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150593 | 0.85 | MRGPRX4 (0.42) | MRGPRX4ACHETAAR1ALDH1A1MAPT | |
| SCHEMBL20150589 | 0.81 | HTR2C (0.43) | MRGPRX4ALDH1A1MAPTHTR1ASLC6A4 | |
| SCHEMBL2558403 | 0.77 | AKR1C3 (0.37) | ACHEALDH1A1MAPTAKR1C3POLB | |
| SCHEMBL2558400 | 0.77 | AKR1C3 (0.37) | ACHEALDH1A1MAPTAKR1C3POLB | |
| SCHEMBL20084267 | 0.77 | L3MBTL1 (0.49) | ALDH1A1MAPTMAPK1L3MBTL1NFE2L2 | |
| SCHEMBL130839 | 0.76 | KDM1A (0.51) | MRGPRX4ACHEALDH1A1MAPTMAPK1 | |
| SCHEMBL13905218 | 0.76 | MRGPRX4 (0.48) | MRGPRX4ACHEALDH1A1MAPTFFAR1 | |
| SCHEMBL16852392 | 0.75 | FFAR4 (0.35) | FFAR1TUBB1 | |
| SCHEMBL8222546 | 0.74 | MAPT (0.44) | ALDH1A1MAPTMAPK1L3MBTL1POLB | |
| SCHEMBL20121313 | 0.74 | AKR1C3 (0.32) | MRGPRX4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134960-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134960-A1 | LIQUID-CRYSTAL MEDIUM | FES, POF1B, FOXO3 | MRGPRX4 4860/4885ACHE 3829/4885TAAR1 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.