Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.54 |
| ▸ | SRC | P12931 | 4/20 | 0.52 |
| ▸ | BTK | Q06187 | 4/20 | 0.52 |
| ▸ | FYN | P06241 | 3/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 9/20 | 0.48 |
| ▸ | BRAF | P15056 | 3/20 | 0.48 |
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.48 |
| ▸ | BLK | P51451 | 1/20 | 0.48 |
| ▸ | BMX | P51813 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20138979 | 0.95 | BTK (0.54) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20139048 | 0.89 | SRC (0.59) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20143667 | 0.85 | PIK3CD (0.56) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20139002 | 0.84 | PIK3CD (0.55) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20139083 | 0.83 | EGFR (0.70) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20150686 | 0.82 | EGFR (0.50) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20146350 | 0.81 | CSF1R (0.49) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20138990 | 0.81 | EGFR (0.54) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20138993 | 0.81 | PIK3CD (0.52) | PIK3CDSRCBTKFYNVCP | |
| SCHEMBL20139785 | 0.81 | SRC (0.58) | PIK3CDSRCBTKPLCG1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018088780-A1 | NOVEL PYRROLOPYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-17 | — | — | WO | disclosed |