SCHEMBL2015158

SCHEMBL2015158

CCC(C)CC1CCCC1=O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 10/20 0.41
PTGS2 P35354 9/20 0.41
KMT2A Q03164 2/20 0.41
OPRK1 P41145 1/20 0.41
HTT P42858 1/20 0.41
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA4 P22748 3/20 0.33
CA6 P23280 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11904307 0.94 CA1 (0.41) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL9720357 0.85 PTGS1 (0.39) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL2691668 0.82 PTGS1 (0.44) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL15876106 0.81 NPC1 (0.41) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL27512692 0.81 PTGS1 (0.39) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL4740919 0.80 PTGS1 (0.38) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL28209530 0.80 PTGS1 (0.39) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL28932789 0.78 PTGS2 (0.45) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL8469486 0.78 PTGS1 (0.43) PTGS1PTGS2KMT2AOPRK1HTT
SCHEMBL4128734 0.77 NOS1 (0.45) PTGS1PTGS2KMT2AOPRK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2487150-B1 PROCESS FOR PRODUCING A LACTONE KAO CORP (JP) 2016-12-28 EP disclosed
CN-102548944-B Process for producing 2-alkylcycloalkanone KAO CORP 2014-12-10 CN disclosed
EP-2487150-A1 PROCESS FOR PRODUCING 2-ALKYLCYCLOALKANONE Kao Corporation (JP) 2012-08-15 EP disclosed
WO-2011073843-A1 ODORANT ALCOHOLS FIRMENICH SA (CH) 2011-06-23 WO disclosed