SCHEMBL2015165

SCHEMBL2015165

c1cnc2ccc3[nH]cnc3c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
MAPT P10636 3/20 0.54
KDM4E B2RXH2 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HTT P42858 2/20 0.46
ALDH1A1 P00352 1/20 0.46
PRNP P04156 1/20 0.46
HPGD P15428 1/20 0.46
CYP3A4 P08684 1/20 0.44
POLB P06746 1/20 0.44
HSP90AA1 P07900 2/20 0.43
HSP90AB1 P08238 1/20 0.43
BLM P54132 1/20 0.43
HIF1A Q16665 1/20 0.43
ACVR1 Q04771 2/20 0.42
PARP1 P09874 4/20 0.42
PSMD14 O00487 1/20 0.41
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30482888 0.98 LMNA (0.55) LMNAMAPTKDM4ESMN1; SMN2MEN1
SCHEMBL168621 0.79 MEN1 (0.53) LMNAMAPTKDM4ESMN1; SMN2MEN1
Benzimidazole SCHEMBL28374782 0.78 LMNA (0.66) LMNAMAPTKDM4ESMN1; SMN2MEN1
SCHEMBL2938806 0.77 PARP1 (0.56) LMNAMAPTKDM4ESMN1; SMN2ACVR1
Benzimidazole SCHEMBL28370588 0.77 LMNA (0.64) LMNAMAPTKDM4ESMN1; SMN2MEN1
Triphenylene SCHEMBL28101738 0.77 LMNA (0.64) LMNAMAPTKDM4ESMN1; SMN2MEN1
SCHEMBL16416550 0.76 LMNA (0.44) LMNAMAPTKDM4ESMN1; SMN2MEN1
SCHEMBL4992901 0.76 LMNA (0.58) LMNAMAPTKDM4ESMN1; SMN2MEN1
SCHEMBL6397525 0.76 LMNA (0.42) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL27971352 0.76 LMNA (0.50) LMNAMAPTKDM4ESMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118434721-A Compounds for use in semiconductor materials suitable for electronic devices 诺瓦尔德股份有限公司 2024-08-02 CN claimed
WO-2023110330-A1 COMPOUNDS FOR USE IN SEMICONDUCTIONG MATERIALS SUITABLE FOR ELECTRONIC DEVICES NOVALED GMBH (DE) 2023-06-22 WO claimed
EP-4198026-A1 COMPOUNDS FOR USE IN SEMICONDUCTIONG MATERIALS SUITABLE FOR ELECTRONIC DEVICES Novaled GmbH (DE) 2023-06-21 EP claimed
WO-2015130900-A1 SYSTEMS, DEVICES, AND METHODS FOR MAKING OR ADMINISTERING FROZEN PARTICLES SEARETE LLC (US) 2015-09-03 WO claimed
US-9072688-B2 Compositions and methods for therapeutic delivery with frozen particles THE INVENTION SCIENCE FUND I, LLC (US) 2015-07-07 US claimed
US-9060934-B2 Compositions and methods for surface abrasion with frozen particles THE INVENTION SCIENCE FUND I, LLC (US) 2015-06-23 US claimed
US-9060926-B2 Compositions and methods for therapeutic delivery with frozen particles THE INVENTION SCIENCE FUND I, LLC (US) 2015-06-23 US claimed
US-9060931-B2 Compositions and methods for delivery of frozen particle adhesives THE INVENTION SCIENCE FUND I, LLC (US) 2015-06-23 US claimed
US-9050317-B2 Compositions and methods for therapeutic delivery with frozen particles THE INVENTION SCIENCE FUND I, LLC (US) 2015-06-09 US claimed
US-9050070-B2 Compositions and methods for surface abrasion with frozen particles THE INVENTION SCIENCE FUND I, LLC (US) 2015-06-09 US claimed
US-8603496-B2 Compositions and methods for biological remodeling with frozen particle compositions THE INVENTION SCIENCE FUND I, LLC (US) 2013-12-10 US claimed
US-8568363-B2 Frozen compositions and methods for piercing a substrate THE INVENTION SCIENCE FUND I, LLC (US) 2013-10-29 US claimed
US-8409376-B2 Compositions and methods for surface abrasion with frozen particles THE INVENTION SCIENCE FUND I, LLC (US) 2013-04-02 US claimed
US-20130071319-A1 Compositions and Methods for Surface Abrasion with Frozen Particles SEARETE LLC (US) 2013-03-21 US claimed
US-20100111844-A1 Compositions and methods for therapeutic delivery with frozen particles SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE 2010-05-06 US claimed
US-20100111845-A1 Compositions and methods for therapeutic delivery with frozen particles SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE 2010-05-06 US claimed
US-20100111843-A1 Compositions and methods for therapeutic delivery with frozen particles SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE 2010-05-06 US claimed
US-20100111842-A1 Compositions and methods for therapeutic delivery with frozen particles SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE 2010-05-06 US claimed
US-4716168-A STIMULANTS OF IMMUNE RESPONSE NORWICH EATON PHARMACEUTICALS, INC. (US) 1987-12-29 US claimed
EP-0187705-A2 Imidazo(4,5-f)quinolines useful as immunomodulating agents Norwich Eaton Pharmaceuticals, Inc. (US) 1986-07-16 EP claimed