Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015172 | 1.00 | MMP8 (0.57) | MMP8HPRT1ELANETP53TACR1 | |
| Hydrochloric Acid SCHEMBL13724226 | 0.98 | MMP8 (0.56) | MMP8HPRT1ELANETP53TACR1 | |
| Hydrochloric Acid SCHEMBL13724224 | 0.98 | MMP8 (0.56) | MMP8HPRT1ELANETP53TACR1 | |
| SCHEMBL20239093 | 0.87 | ATM (0.61) | POLBALDH1A1GAARAB9AATM | |
| SCHEMBL20239092 | 0.87 | ATM (0.61) | POLBALDH1A1GAARAB9AATM | |
| SCHEMBL15343891 | 0.85 | MMP8 (0.59) | MMP8HPRT1ELANETP53TACR1 | |
| SCHEMBL8966036 | 0.85 | MMP8 (0.59) | MMP8HPRT1ELANETP53TACR1 | |
| SCHEMBL27464748 | 0.85 | MMP8 (0.59) | MMP8HPRT1ELANETP53TACR1 | |
| SCHEMBL4765072 | 0.85 | MMP8 (0.59) | MMP8HPRT1ELANETP53TACR1 | |
| SCHEMBL6322057 | 0.85 | MMP8 (0.59) | MMP8HPRT1ELANETP53TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4083052-A1 | PEPTIDE CONJUGATES OF MELPHALAN FOR THE TREATMENT OF CANCER | BKmdcl AB (SE) | 2022-11-02 | — | — | EP | disclosed |
| EP-3280721-A1 | PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES | Oncopeptides AB (SE) | 2018-02-14 | — | — | EP | disclosed |
| WO-2016180740-A1 | PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES | ONCOPEPTIDES AB (SE) | 2016-11-17 | — | — | WO | disclosed |
| EP-2928463-A1 | LYOPHILIZED PREPARATIONS OF MELPHALAN FLUFENAMIDE | Oncopeptides AB (SE) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014065751-A1 | LYOPHILIZED PREPARATIONS OF MELPHALAN FLUFENAMIDE | ONCOPEPTIDES AB (SE) | 2014-05-01 | — | — | WO | disclosed |
| EP-2701720-A1 | LYOPHILIZED PREPARATION OF CYTOTOXIC DIPEPTIDES | Oncopeptides AB (SE) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012146625-A1 | LYOPHILIZED PREPARATION OF CYTOTOXIC DIPEPTIDES | ONCOPEPTIDES AB (SE) | 2012-11-01 | — | — | WO | disclosed |
| WO-2011078782-A1 | A COMPOSITION COMPRISING OF MELPHALAN DERIVATIVES AND GEMCITABINE OR ETOPOSIDE USEFUL IN THE TREATMENT OF CANCER | ONCOPEPTIDES AB (SE) | 2011-06-30 | — | — | WO | disclosed |
| CN-1155611-C | Endothelin antagon | 中国人民解放军军事医学科学院毒物药 | 2004-06-30 | — | — | CN | disclosed |