SCHEMBL20239093

SCHEMBL20239093

COC(=O)C(Cc1ccccc1)NF

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.61
ALDH1A1 P00352 2/20 0.60
THRB P10828 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
HSD17B10 Q99714 1/20 0.60
POLB P06746 2/20 0.58
CA12 O43570 2/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
CA14 Q9ULX7 2/20 0.56
CA2 P00918 1/20 0.56
LMNA P02545 1/20 0.56
GLA P06280 1/20 0.56
ANPEP P15144 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
NOS3 P29474 1/20 0.54
NOS1 P29475 1/20 0.54
NOS2 P35228 1/20 0.54
GAA P10253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20239092 1.00 ATM (0.61) ATMALDH1A1THRBCYP2C9CYP2C19
Hydrochloric Acid SCHEMBL27714987 0.98 ATM (0.60) ATMALDH1A1THRBCYP2C9CYP2C19
Hydrochloric Acid SCHEMBL27714985 0.98 ATM (0.60) ATMALDH1A1THRBCYP2C9CYP2C19
SCHEMBL2015172 0.87 MMP8 (0.57) ATMALDH1A1THRBCYP2C9CYP2C19
SCHEMBL2015170 0.87 MMP8 (0.57) ATMALDH1A1THRBCYP2C9CYP2C19
SCHEMBL2015772 0.85 TSHR (0.50) ATMALDH1A1THRBCYP2C9CYP2C19
Hydrochloric Acid SCHEMBL13724224 0.85 MMP8 (0.56) ATMALDH1A1THRBCYP2C9CYP2C19
Hydrochloric Acid SCHEMBL13724226 0.85 MMP8 (0.56) ATMALDH1A1THRBCYP2C9CYP2C19
SCHEMBL2015774 0.85 TSHR (0.50) ATMALDH1A1THRBCYP2C9CYP2C19
SCHEMBL28858146 0.85 ATM (0.57) ATMALDH1A1THRBCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 US disclosed
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2024-04-18 US disclosed
US-11891422-B2 NEMO coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2024-02-06 US disclosed
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME CORNELL UNIVERSITY 2022-09-15 US disclosed
US-11440938-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2022-09-13 US disclosed
US-20210277059-A1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2021-09-09 US disclosed
US-10851133-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2020-12-01 US disclosed
US-20200190155-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2020-06-18 US disclosed
US-20180162907-A1 STABILIZED MINIMAL COILED-COIL MIMETICS NEW YORK UNIVERSITY 2018-06-14 US disclosed
CN-108047304-A - 7 selective depressant of metalloproteinases and its preparation method and application 延边大学 2018-05-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH ATM 4455/4885ALDH1A1 3890/4885THRB 1310/4885
US-11440938-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, SMC2 ATM 2538/4885ALDH1A1 4826/4885THRB 1869/4885
US-10851133-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, CRYZ ATM 2552/4885ALDH1A1 4832/4885THRB 1717/4885
US-20210277059-A1 STABILIZED MINIMAL COILED-COIL MIMETICS COIL, CALCOCO2, CRYZ ATM 2552/4885ALDH1A1 4832/4885THRB 1717/4885
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME SOS2, SOS1, F2 ATM 4275/4885ALDH1A1 3199/4885THRB 560/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 ATM 4453/4885ALDH1A1 4748/4885THRB 709/4885
US-11891422-B2 NEMO coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH ATM 4455/4885ALDH1A1 3890/4885THRB 1310/4885
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH ATM 4455/4885ALDH1A1 3890/4885THRB 1310/4885
US-20200190155-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH ATM 4455/4885ALDH1A1 3890/4885THRB 1310/4885
US-20180162907-A1 STABILIZED MINIMAL COILED-COIL MIMETICS COIL, CALCOCO2, CRYZ ATM 2552/4885ALDH1A1 4832/4885THRB 1717/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH ATM 4377/4885ALDH1A1 3702/4885THRB 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.