Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 19/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20136971 | 0.91 | MGLL (1.00) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20151767 | 0.83 | MGLL (0.69) | MGLL | |
| SCHEMBL20151759 | 0.82 | MGLL (0.84) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20150063 | 0.77 | MGLL (0.51) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20150055 | 0.77 | MGLL (0.52) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20150052 | 0.76 | MGLL (0.53) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20151811 | 0.75 | MGLL (0.81) | MGLL | |
| SCHEMBL19628024 | 0.73 | MGLL (0.57) | MGLLKDM4EALDH1A1POLBPLA2G7 | |
| SCHEMBL20136977 | 0.73 | MGLL (1.00) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20137065 | 0.73 | MGLL (1.00) | MGLLPLA2G7ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | MGLL 3/4885KDM4E 984/4885ALDH1A1 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.