SCHEMBL20152175

SCHEMBL20152175

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5c6c7ccccc7n(-c7ccc(-c8nc9ccccc9nc8-c8ccccc8)cc7)c6ccc54)cc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
ATM Q13315 2/20 0.46
KDM4E B2RXH2 5/20 0.42
L3MBTL1 Q9Y468 5/20 0.42
LMNA P02545 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
GAA P10253 2/20 0.42
ALDH1A1 P00352 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
AKT1 P31749 1/20 0.38
AKT2 P31751 1/20 0.38
POLB P06746 1/20 0.37
HSD17B10 Q99714 1/20 0.37
DHODH Q02127 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.37
HPGD P15428 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152177 0.96 KMT2A (0.43) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL20152156 0.95 KDM4E (0.46) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL20152181 0.94 MEN1 (0.52) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL19653957 0.93 L3MBTL1 (0.47) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL20152190 0.93 KMT2A (0.40) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL19653937 0.92 L3MBTL1 (0.46) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL18846130 0.91 KMT2A (0.46) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL20152206 0.91 ATM (0.58) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL12690987 0.90 L3MBTL1 (0.48) KMT2AMEN1ATMKDM4EL3MBTL1
SCHEMBL20152161 0.90 ATM (0.56) KMT2AMEN1ATMKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 KMT2A 3996/4885MEN1 4244/4885ATM 2986/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 KMT2A 3996/4885MEN1 4244/4885ATM 2986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.