SCHEMBL20152191

SCHEMBL20152191

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5c6c7ccccc7n(-c7cnc8c9ccccc9c9ccccc9c8n7)c6ccc54)cc3)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.35
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 2/20 0.31
MAPT P10636 1/20 0.31
PTK2B Q14289 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TLR7 Q9NYK1 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653812 0.94 L3MBTL1 (0.37) ATMKDM4EL3MBTL1KMT2AMAPT
SCHEMBL18124871 0.94 L3MBTL1 (0.37) ATMKDM4EL3MBTL1KMT2AMAPT
SCHEMBL20152180 0.91 TLR7 (0.32) MAPTTLR7
SCHEMBL19653787 0.89 KDM4E (0.45) ATMKDM4EL3MBTL1KMT2AMAPT
SCHEMBL20152183 0.86 KMT2A (0.33) ATMKDM4EL3MBTL1KMT2AMAPT
SCHEMBL18124893 0.85 KDM4E (0.34) ATMKDM4EL3MBTL1KMT2AMEN1
SCHEMBL19655108 0.85 GABRP (0.38) ATMKDM4EL3MBTL1KMT2AMAPT
SCHEMBL19653788 0.85 KDM4E (0.33) ATMKDM4EL3MBTL1
SCHEMBL19653820 0.85 KDM4E (0.42) ATMKDM4EL3MBTL1KMT2AMEN1
SCHEMBL20152271 0.85 L3MBTL1 (0.34) ATMKDM4EL3MBTL1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 ATM 2986/4885KDM4E 3377/4885L3MBTL1 2317/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 ATM 2986/4885KDM4E 3377/4885L3MBTL1 2317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.