Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18896226 | 1.00 | KDM4E (1.00) | KDM4EKMT2ANAAAHDAC3HDAC1 | |
| SCHEMBL3924178 | 1.00 | KDM4E (1.00) | KDM4EKMT2ANAAAHDAC3HDAC1 | |
| SCHEMBL3614618 | 1.00 | KDM4E (1.00) | KDM4EKMT2ANAAAHDAC3HDAC1 | |
| SCHEMBL9755022 | 0.98 | KDM4E (0.97) | KDM4EKMT2ANAAAHDAC3HDAC1 | |
| SCHEMBL27650606 | 0.94 | KDM4E (0.89) | KDM4EKMT2ANAAAHDAC3HDAC1 | |
| SCHEMBL6359528 | 0.94 | KDM4E (0.88) | KDM4EKMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6360168 | 0.87 | KDM4E (0.77) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| Formamide SCHEMBL8056562 | 0.87 | KDM4E (0.77) | KDM4EKMT2AHDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL30096713 | 0.84 | KDM4E (0.72) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5656679 | 0.84 | KDM4E (0.72) | KDM4EKMT2AHDAC3HDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240748-A1 | IMPROVED METHOD FOR THE FORMATION OF AMIDES | BASF SE (DE) | 2024-11-28 | — | — | WO | disclosed |
| US-10369140-B2 | Aryl dihydropyridinones and piperidinone MGAT2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180133198-A1 | ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133198-A1 | ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS | DGAT2, MGAT2, MGAT1 | KDM4E 1993/4885KMT2A 155/4885NAAA 268/4885 |
| US-10369140-B2 | Aryl dihydropyridinones and piperidinone MGAT2 inhibitors | DGAT2, MGAT2, MGAT1 | KDM4E 1993/4885KMT2A 155/4885NAAA 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.