Sugi Predict

Sugi Predict / Compounds / SCHEMBL20152308

SCHEMBL20152308

SCHEMBL20152308

CC1(C)c2ccccc2N2c3ccccc3-c3ccccc3-c3cccc1c32

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 4/20 0.38
▸ LMNA P02545 2/20 0.38
▸ KMT2A Q03164 8/20 0.38
▸ MEN1 O00255 7/20 0.38
▸ PGR P06401 5/20 0.38
▸ CYP2D6 P10635 2/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ MAPT P10636 8/20 0.36
▸ GAA P10253 2/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ NPC1 O15118 2/20 0.34
▸ POLB P06746 2/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ USP2 O75604 2/20 0.34
▸ THRB P10828 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12333544 0.85 KMT2A (0.43) HTTLMNAKMT2AMEN1PGR
SCHEMBL20444651 0.84 PDE6D (0.38) HTTKMT2AMEN1PGRCYP2D6
SCHEMBL15434752 0.83 KMT2A (0.42) HTTLMNAKMT2AMEN1PGR
SCHEMBL20444406 0.82 KMT2A (0.36) HTTLMNAKMT2AMEN1PGR
SCHEMBL19885317 0.81 HTT (0.33) HTTLMNAKMT2AMEN1PGR
SCHEMBL15434809 0.80 MGLL (0.41) HTTLMNAKMT2AMEN1PGR
SCHEMBL15434753 0.80 KMT2A (0.42) HTTLMNAKMT2AMEN1PGR
SCHEMBL16389350 0.79 NPSR1 (0.38) HTTLMNAKMT2AMEN1PGR
SCHEMBL12281541 0.79 KMT2A (0.39) HTTLMNAKMT2AMEN1PGR
SCHEMBL20444409 0.77 AR (0.35) KMT2AMEN1PGRCYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10844059-B2 Heterocyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-24 — — US disclosed
US-10636979-B2 Heterocyclic compounds with dibenzazapine structures MERCK PATENT GMBH (DE) 2020-04-28 — — US disclosed
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 — — US disclosed
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10636979-B2 Heterocyclic compounds with dibenzazapine structures DDT, MAOA, MAOB HTT 568/4885LMNA 1577/4885KMT2A 678/4885
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME OR10J3, HDAC10, RBM12 HTT 3050/4885LMNA 3768/4885KMT2A 1167/4885
US-10844059-B2 Heterocyclic compound and organic electroluminescence device including the same OR10J3, HDAC10, RBM12 HTT 3050/4885LMNA 3768/4885KMT2A 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.