SCHEMBL20152310

SCHEMBL20152310

c1ccc(C2(c3ccccc3)c3cc(-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4cccc6c4N5c4ccccc4-c4ccccc4-6)ccc3N3c4ccccc4-c4ccccc4-c4cccc2c43)cc1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152306 0.89 LMNA (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL12109062 0.87 LMNA (0.30) LMNA
SCHEMBL20152307 0.87 MEN1 (0.35) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL20152335 0.86
SCHEMBL20152312 0.81 MCL1 (0.35)
SCHEMBL20152317 0.79 PDK2 (0.38) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL25495732 0.77 PDK2 (0.39) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL12109064 0.77 ALDH1A1 (0.35) LMNA
SCHEMBL13371830 0.76 PDK2 (0.35) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL19035959 0.76 LMNA (0.36) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10844059-B2 Heterocyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-24 US disclosed
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 US disclosed
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME OR10J3, HDAC10, RBM12 PDK2 1425/4885KDM4E 565/4885MEN1 2863/4885
US-10844059-B2 Heterocyclic compound and organic electroluminescence device including the same OR10J3, HDAC10, RBM12 PDK2 1425/4885KDM4E 565/4885MEN1 2863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.