SCHEMBL20152333

SCHEMBL20152333

c1ccc2c(c1)-c1ccccc1N1c3ccc(-c4ccc5c(c4)Sc4cccc6c4N5c4ccccc4-c4ccccc4-6)cc3Sc3cccc-2c31

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MEN1 O00255 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
CHRM3 P20309 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
SLC6A4 P31645 1/20 0.36
DRD3 P35462 1/20 0.36
HTR2B P41595 1/20 0.36
KMT2A Q03164 1/20 0.36
MAOA P21397 1/20 0.33
SNCA P37840 1/20 0.32
ALDH1A1 P00352 1/20 0.31
BCHE P06276 4/20 0.31
HPGD P15428 1/20 0.31
HDAC6 Q9UBN7 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152318 0.84 MEN1 (0.37) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL20152334 0.79 MCL1 (0.35) BCHEHDAC6
SCHEMBL20152320 0.79 L3MBTL1 (0.34) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL20152321 0.76 KDM4E (0.32) L3MBTL1
SCHEMBL20152331 0.75 HSP90AA1 (0.36) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL21942387 0.72 KDM4E (0.33) NOX1L3MBTL1MEN1KMT2AMAOA
SCHEMBL10331700 0.72 HDAC6 (0.46) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL14244233 0.72 MAOA (0.54) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL29824891 0.72 MAOA (0.54) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL13314104 0.72 CES1 (0.39) L3MBTL1MEN1KMT2AMAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10844059-B2 Heterocyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-24 US disclosed
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 US disclosed
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME OR10J3, HDAC10, RBM12 NOX1 245/4885L3MBTL1 2661/4885MEN1 2863/4885
US-10844059-B2 Heterocyclic compound and organic electroluminescence device including the same OR10J3, HDAC10, RBM12 NOX1 245/4885L3MBTL1 2661/4885MEN1 2863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.