Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365181 | 1.00 | SKP2 (0.66) | SKP2TAAR1CYP1A2CYP2A6TDP1 | |
| Ammonia Solution, Strong SCHEMBL5929377 | 0.98 | SKP2 (0.63) | SKP2TAAR1CYP1A2CYP2A6TDP1 | |
| SCHEMBL841783 | 0.89 | SKP2 (0.73) | SKP2CYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL31634603 | 0.89 | SKP2 (0.73) | SKP2CYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL23093003 | 0.88 | SKP2 (0.72) | SKP2TAAR1CYP1A2CYP2A6TDP1 | |
| SCHEMBL3482834 | 0.86 | SKP2 (0.70) | SKP2TAAR1CYP1A2CYP2A6TDP1 | |
| Sulfuric Acid SCHEMBL8474234 | 0.85 | SKP2 (0.54) | SKP2TAAR1CYP1A2CYP2A6TDP1 | |
| SCHEMBL3514830 | 0.84 | SKP2 (0.81) | SKP2CYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL7747145 | 0.83 | SKP2 (0.78) | SKP2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL28125839 | 0.83 | SKP2 (0.78) | SKP2TDP1ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979893-B | N-hydroxy formamidine derivative, preparation method and application | 中国药科大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-113979893-A | N-hydroxyformamidine derivative, preparation method and application | 中国药科大学 | 2022-01-28 | — | — | CN | disclosed |
| US-8648201-B2 | Aminopyridine derivatives for treating tumors and inflammatory diseases | MERCK PATENT GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |