SCHEMBL7747145

SCHEMBL7747145

CCCc1ccc(N)c(C)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.78
ALDH1A1 P00352 2/20 0.48
CYP3A4 P08684 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 1/20 0.48
S100B P04271 1/20 0.47
CNR1 P21554 1/20 0.45
CNR2 P34972 1/20 0.45
ESR1 P03372 2/20 0.43
AR P10275 1/20 0.42
ESR2 Q92731 1/20 0.42
FFAR4 Q5NUL3 1/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
MAPT P10636 1/20 0.40
GFER P55789 1/20 0.40
GAA P10253 1/20 0.40
RAD52 P43351 1/20 0.40
CA2 P00918 1/20 0.39
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31634603 0.89 SKP2 (0.73) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL841783 0.89 SKP2 (0.73) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL4638583 0.88 SKP2 (1.00) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL3482834 0.86 SKP2 (0.70) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL22604978 0.86 SKP2 (0.89) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL3514830 0.84 SKP2 (0.81) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL11869178 0.84 SKP2 (0.86) SKP2ALDH1A1CYP3A4ESR1RAB9A
SCHEMBL4198843 0.83 SKP2 (0.55) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL29365181 0.83 SKP2 (0.66) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL28125839 0.83 SKP2 (0.78) SKP2ALDH1A1CYP3A4TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5306828-A Catalytic imidation of malic anhydride with amine in solvent mixture BROMINE COMPOUNDS LTD. (IL) 1994-04-26 US claimed
EP-0499959-A1 Process for the manufacture of substituted maleimides Bromine Compounds Ltd. (IL) 1992-08-26 EP claimed
CN-118250904-A Method for manufacturing circuit board 味之素株式会社 2024-06-25 CN disclosed
CN-111560171-B Resin composition 味之素株式会社 2024-06-18 CN disclosed
CN-118176259-A Dispersion of carbon nanotubes, coating liquid composition for electrode using same, electrode, and lithium ion secondary battery 第一工业制药株式会社 2024-06-11 CN disclosed
CN-118063932-A Resin composition 味之素株式会社 2024-05-24 CN disclosed
CN-111548625-B Resin composition 味之素株式会社 2024-04-05 CN disclosed
CN-117693545-A Organosilicon polymer compound and organosilicon polymer material 国立大学法人大阪大学 2024-03-12 CN disclosed
CN-111138856-B Resin composition 味之素株式会社 2024-01-23 CN disclosed
CN-114621118-B Lignin-based diphenylmethane diisocyanate and application thereof in preparation of polyurethane material 南京工业大学 2023-12-01 CN disclosed
CN-115650861-B Application of lignin-based polyurethane chain extender in preparation of polyurethane material 南京工业大学 2023-11-24 CN disclosed
US-20100298298-A1 QUINAZOLINEDIONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI-AVENTIS (FR) 2010-11-25 US disclosed
CN-101674923-A Process and apparatus for production of colorless transparent resin film MITSUBISHI GAS CHEMICAL CO 2010-03-17 CN disclosed
EP-1064329-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2001-01-03 EP disclosed
EP-1064319-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2001-01-03 EP disclosed
WO-1999033902-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed
WO-1999033923-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed
US-5306828-A Catalytic imidation of malic anhydride with amine in solvent mixture BROMINE COMPOUNDS LTD. (IL) 1994-04-26 US disclosed
EP-0499959-A1 Process for the manufacture of substituted maleimides Bromine Compounds Ltd. (IL) 1992-08-26 EP disclosed
US-4173645-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298298-A1 QUINAZOLINEDIONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF PPARD, DPP4, NDUFB7 SKP2 1653/4885ALDH1A1 636/4885CYP3A4 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.