SCHEMBL841783

SCHEMBL841783

Cc1cc(CCc2ccc(N)c(C)c2)ccc1N

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.73
ALDH1A1 P00352 5/20 0.54
CYP3A4 P08684 4/20 0.54
TDP1 Q9NUW8 3/20 0.54
TSHR P16473 2/20 0.54
S100B P04271 1/20 0.47
GFER P55789 1/20 0.42
MAPK1 P28482 1/20 0.42
ESR1 P03372 1/20 0.41
AR P10275 1/20 0.41
ESR2 Q92731 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
CYP19A1 P11511 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
RAD52 P43351 1/20 0.40
ALOX15 P16050 2/20 0.39
HIF1A Q16665 2/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31634603 1.00 SKP2 (0.73) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL3482834 0.98 SKP2 (0.70) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL3514830 0.91 SKP2 (0.81) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL29365181 0.89 SKP2 (0.66) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL2015277 0.89 SKP2 (0.66) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL28125839 0.89 SKP2 (0.78) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL7747145 0.89 SKP2 (0.78) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL8086634 0.87 SKP2 (0.58) SKP2ALDH1A1CYP3A4TDP1TSHR
SCHEMBL3775339 0.87 SKP2 (0.63) SKP2ALDH1A1CYP3A4TDP1TSHR
Ammonia Solution, Strong SCHEMBL5929377 0.87 SKP2 (0.63) SKP2ALDH1A1CYP3A4TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024150597-A1 THERMOSETTING RESIN COMPOSITION, CURED FILM, SUBSTRATE, AND ELECTRONIC COMPONENT JNC株式会社 2024-07-18 WO disclosed
EP-3125033-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2021-06-02 EP disclosed
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer JNC CORPORATION (JP) 2021-04-06 US disclosed
US-10782566-B2 Liquid crystal display device JNC CORPORATION (JP) 2020-09-22 US disclosed
WO-2020162408-A1 METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE セントラル硝子株式会社 2020-08-13 WO disclosed
EP-3179303-B1 LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2020-04-01 EP disclosed
US-10435627-B2 Liquid crystal display device JNC CORPORATION (JP) 2019-10-08 US disclosed
US-10437107-B2 Liquid-crystal display element DIC CORPORATION (JP) 2019-10-08 US disclosed
US-10423033-B2 Method for producing liquid crystal alignment film and liquid crystal display element using same DIC CORPORATION (JP) 2019-09-24 US disclosed
EP-3133136-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-08-07 EP disclosed
US-6746730-B1 VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT CHISSO CORPORATION (JP) 2004-06-08 US disclosed
US-6685997-B1 SOLUTION CONTAINING POLYAMIC ACIDS, POLYAMIDES AND POLYIMIDES; ALIGNMENT FILM; WELL BALANCED ELECTRICAL CHARACTERISTICS; ELIMINATES IMAGE STICKING CHISSO CORPORATION (JP) 2004-02-03 US disclosed
US-6620339-B1 Providing polyimide resin with large pretilt angle; small residual voltage and high voltage holding ratio; reliable CHISSO CORPORATION (JP) 2003-09-16 US disclosed
EP-1064319-B1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORP (JP) 2003-02-19 EP disclosed
US-6316574-B1 FOR PRODUCING ALIGNING FILMS, PROTECTION FILMS, INSULATION FILMS ELECTRICAL PROPERTIES AND RELIABILITY; FOR USE IN ELECTRONIC MATERIALS CHISSO CORPORATION (JP) 2001-11-13 US disclosed
EP-1042701-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2000-10-11 EP disclosed
WO-1999034252-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed
EP-0424860-B1 Wholly aromatic polyamides, process for their preparation and products therefrom HOECHST AG (DE) 1993-12-01 EP disclosed
US-5097015-A Fibers, filaments, films and sheets HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-17 US disclosed
EP-0424860-A2 Wholly aromatic polyamides, process for their preparation and products therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer DDT, DCLRE1A, DVL1 SKP2 1187/4885ALDH1A1 2734/4885CYP3A4 4542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.