Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20152947 | 0.91 | ALOX5 (0.49) | TTRALOX5KMT2AMEN1ALDH1A1 | |
| SCHEMBL20152943 | 0.86 | HSD17B10 (0.45) | KMT2AMEN1BACE1 | |
| SCHEMBL3208961 | 0.85 | ALOX5 (0.55) | TTRALOX5KMT2AMEN1ALDH1A1 | |
| SCHEMBL20152931 | 0.84 | TTR (0.44) | TTRALOX5KMT2AMEN1ALDH1A1 | |
| SCHEMBL20152975 | 0.81 | NPSR1 (0.40) | BACE1 | |
| SCHEMBL5034496 | 0.79 | BACE1 (0.48) | TTRKMT2AMEN1ALDH1A1BACE1 | |
| SCHEMBL20152938 | 0.79 | SLC13A5 (0.37) | TTRKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL20152889 | 0.79 | ALOX5 (0.48) | TTRALOX5ALDH1A1 | |
| SCHEMBL6035879 | 0.75 | CYP4F2 (0.50) | TTRKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL7332981 | 0.75 | HSD17B10 (0.63) | NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |