Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20152947 | 0.92 | ALOX5 (0.49) | TTRALOX5MEN1KMT2ABACE1 | |
| SCHEMBL20152915 | 0.87 | NPSR1 (0.47) | — | |
| SCHEMBL3208961 | 0.86 | ALOX5 (0.55) | TTRALOX5MEN1KMT2ABACE1 | |
| SCHEMBL20152905 | 0.84 | TTR (0.43) | TTRALOX5MEN1KMT2ABACE1 | |
| SCHEMBL5034496 | 0.80 | BACE1 (0.48) | TTRMEN1KMT2ABACE1KDM4E | |
| SCHEMBL20152889 | 0.80 | ALOX5 (0.48) | TTRALOX5KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28910439 | 0.80 | IAPP (0.50) | — | |
| SCHEMBL6035879 | 0.79 | CYP4F2 (0.50) | TTRMEN1KMT2APOLBKDM4E | |
| SCHEMBL20152975 | 0.79 | NPSR1 (0.40) | BACE1HSD17B10 | |
| SCHEMBL20152924 | 0.79 | CHRNA7 (0.42) | ALDH1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |