Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20152937 | 0.86 | LTB4R (0.38) | LTB4RLTB4R2 | |
| SCHEMBL20152903 | 0.85 | BACE1 (0.42) | LTB4RLTB4R2ESR2HPGDTHRB | |
| SCHEMBL20153001 | 0.80 | BACE1 (0.41) | LTB4RLTB4R2FYNALOX15MEN1 | |
| SCHEMBL20153011 | 0.78 | IAPP (0.40) | TRPM8ESR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL20152874 | 0.68 | ESR2 (0.48) | ESR2MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL26823126 | 0.67 | MGLL (0.43) | FYNTRPM8ESR2MAPTSMN1; SMN2 | |
| SCHEMBL26823123 | 0.67 | MGLL (0.41) | FYNTRPM8ESR2MAPTSMN1; SMN2 | |
| SCHEMBL20152897 | 0.67 | ESR1 (0.33) | ESR2 | |
| SCHEMBL20152917 | 0.65 | ESR2 (0.46) | ESR2HSD17B1HSP90AA1 | |
| SCHEMBL16428977 | 0.65 | ESR2 (0.53) | FYNESR2MAPTSMN1; SMN2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |